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Journal: International Journal of Molecular Sciences
Article Title: Liver-Specific Overexpression of Prostasin Attenuates High-Fat Diet-Induced Metabolic Dysregulation in Mice
doi: 10.3390/ijms22158314
Figure Lengend Snippet: Serum PRSS8 levels was negatively associated with the presence of type 2 diabetes and increased intima media thickness. ( a ) The ELISA of human PRSS8 levels in the serum of the nondiabetes mellitus (non-DM) and type 2 diabetes mellitus (T2DM) participants (n = 39–40 per group). Values are shown as the mean ± SEM; * p -value < 0.05 ( t test). ( b ) The maximum intima media thickness (max IMT) measured by carotid ultrasonography in T2DM. Values are shown as the mean ± SEM; ** p -value < 0.01 ( t test). ( c ) Homeostatic model assessment beta cell function (HOMA-β) in non-DM was shown (Pearson product-moment correlation coefficient).
Article Snippet: Measurement of serum fasting PRSS8 levels in WT/LTg mice was used by
Techniques: Enzyme-linked Immunosorbent Assay, Cell Function Assay